Upstream investment partners is a venture capital and growth equity firm focused on investing in early stage technology companies. Based in Palo Alto, California, Upstream partners was founded in 2008 and has since invested in over 60 companies across consumer internet, cloud infrastructure, healthcare IT, fintech and cybersecurity sectors. With over $1 billion in assets under management, Upstream partners targets investments ranging from seed stage to growth equity in companies based primarily in Silicon Valley. Some of their key portfolio companies include Reddit, Oscar Health, Gradescope, Benchling and many more. In this article, we will take a closer look at Upstream’s investment thesis, sectors of interest, portfolio companies as well as founders and investment professionals behind the firm.

Upstream partners focuses on early stage companies in high growth technology sectors
As a Silicon Valley based venture capital firm, Upstream partners’ core investment thesis revolves around identifying and investing early into promising technology companies. Specifically, the firm looks to invest in sectors with strong tailwinds for growth such as consumer internet, cloud infrastructure, artificial intelligence, cybersecurity, fintech and digital health. Within these broad categories, the Upstream team pays close attention to emerging technology trends and paradigms shifts that can give rise to billion dollar companies. For instance, the popularity of smart phones and mobile internet created opportunities in sectors like on-demand services, social media and mobile gaming. Upstream partners aims to identify similar pockets of innovation and change early on. The firm invests anywhere from seed stage to Series B primarily, with occasional later stage investments in standout companies from their portfolio.
Upstream has backed over 60 companies including multiple unicorns like Reddit and Oscar Health
Since its inception, Upstream partners has deployed over $1 billion into promising technology startups across North America. Their portfolio consists of over 60 active companies with a focus on the West Coast technology ecosystem. Some of their marquee investments include Reddit, Oscar Health, Benchling, Gradescope, Opendoor, yesterday and many more. Several of these companies have gone to become technology unicorns with billion dollar plus valuations. For instance, Reddit raised over $550 million before going public in 2021 at a $10 billion valuation. Oscar Health and Opendoor too went public through SPAC mergers valuing them at over $7 billion each. Upstream partners’ success with multiple unicorn companies underscores the firms ability to identify quality early stage deals. Going forward, Upstream plans to maintain its focus on early stage while expanding geographical mandates beyond just Silicon Valley.
The Upstream team combines operational experience and venture capital expertise
Upstream investment partners was founded in 2008 by veterans of Silicon Valley’s technology and investment ecosystem. The firm has 8 partners led by managing partner Yoichiro Taku. Yoichiro spent over a decade in senior product and operations roles at Google before entering venture capital full time. His operating experience allows him to better guide and support Upstream’s portfolio companies. Other partners like Dan Ni comes from an engineering background having led teams at Apple and Nvidia. While still relatively young, the Upstream team has established a strong track record by combining operational experience and venture capital expertise. They have frequently co-invested with top tier firms like Sequoia, Benchmark, Greylock and Lightspeed Venture Partners. Going forward, Upstream plans to leverage its Silicon Valley network and expertise to continue backing promising early stage startups.
In summary, Upstream investment partners is a Silicon Valley based venture capital firm focused on early stage technology companies. With over $1 billion in assets under management and 60+ portfolio companies, Upstream has established itself as a prominent investor in the next generation of technology unicorns.